A recent World Neurosurgery retrospective study has highlighted the innovative use of BloodSTOP® iX in neurosurgery, specifically for managing small dural defects following endoscopic third ventriculostomy (ETV). The study, titled “A Simple Technique of Cerebrospinal Fluid Leak Prevention Following Endoscopic Third Ventriculostomy: A Technical Note”, introduced a novel, suture-free technique that applies BloodSTOP iX as both an inlay and onlay for small dural closure when watertight dural primary closure is not technically feasible using traditional primary dural suturing. The study was conducted at two research sites, Republican Scientific-Practical Medical Center of Neurosurgery and the Tashkent State Pediatric Medical Institute, both of which are located in Tashkent, Uzbekistan (Original Article).
BloodSTOP iX is a plant-based, water-soluble Etherified Carboxymethyl Cellulose (eCMC) matrix. In this study, it was observed to form a translucent gel upon contact with cerebrospinal fluid (CSF), which appeared to support dural closure without obstructing visual monitoring of the site. While the precise mechanism by which BloodSTOP iX may contribute to CSF leakage control has not yet been established, these preliminary findings suggest its potential to address one of neurosurgery’s significant challenges: reducing the risk of CSF leaks and their associated complications.
The study reported outstanding outcomes: no postoperative CSF leaks or sealant‑related complications were observed among patients treated with this technique. Surgeons noted the material’s ease of use, safety, and cost‑efficiency, reinforcing its value as a practical alternative to traditional suturing methods.
BloodSTOP iX is already recognized for its rapid hemostasis and wound-healing benefits in burn and trauma surgery. These research findings highlight a promising new potential application for BloodSTOP iX in neurosurgery, offering surgeons a powerful tool to enhance patient outcomes and reduce complication rates.
BloodSTOP iX – Statements of Intended Use:
US – Emergency and therapeutic use in the control of bleeding from the skin and other surface wounds where temporary control of bleeding is required.
EU – Invasive use, wholly absorbable, for the control of bleeding during and after clinical intervention. Intended for the general population (all ages) and for those on anti-coagulation medication.